Pioneers in Virology.

Walter Reed (1851-1902) Imperial Bacteriology Institute c o r r e c t l y d e m o n s t r a t e d t h a t the etiological agent of rabies was not a protozoan, but a filterable virus a n d t h e a r g u m e n t a b o u t t h e s ignif icance of Negri ’s bodies became wider and more intense, w i t h e m i n e n t p a r a s i t o l o g i s t s taking conflicting positions. For many years, documentation of Negri bodies were the hallmark of rabies. Even today, despite research with the electron microscope, the significance of Negri’s bodies has not been definitively clarified. In 1912, at the age of thirty-five, Negri died of tuberculosis.